Conditions

The Counsyl Reliant Cancer Screen can look at up to 36 specific genes associated with a risk for many different kinds of cancer ― breast, ovarian, colon, pancreatic, prostate, thyroid, and others.

View available panels

Gene Associated syndrome Breast Ovarian Endometrial Colorectal Pancreatic Gastric Prostate Thyroid Melanoma Neuroendocrine
Comprehensive Panel genes
X = Associated cancer risk, O = Associated cancer risk with limited or conflicting evidence
APC Familial adenomatous polyposis x x x x
ATM ATM-associated hereditary cancer x x
BMPR1A Juvenile polyposis x x
BRCA1 BRCA-related breast and ovarian cancer syndrome x x o o
BRCA2 BRCA-related breast and ovarian cancer syndrome x x x x x
BRIP1 BRIP1-associated hereditary cancer x
CDH1 Hereditary diffuse gastric cancer x x x
CDK4 Familial Atypical Multiple Mole Melanoma (FAMMM) syndrome x
CDKN2A Familial Atypical Multiple Mole Melanoma (FAMMM) syndrome x x
CHEK2 CHEK2-associated hereditary cancer x x
EPCAM Lynch syndrome x x x x x
GREM1 Hereditary mixed polyposis syndrome (HMPS) x
MLH1 Lynch syndrome x x x x x
MSH2 Lynch syndrome x x x x x
MSH6 Lynch syndrome x x x x x
MUTYH MUTYH-associated polyposis x
NBN NBN-associated hereditary cancer x
PALB2 PALB2-associated hereditary cancer x x
PMS2 Lynch syndrome x x x x x
POLD1 Polymerase proofreading associated polyposis (PPAP) syndrome o x
POLE Polymerase proofreading associated polyposis (PPAP) syndrome x
PTEN PTEN hamartoma tumor syndrome x x x x
RAD51C RAD51C-associated hereditary cancer x
RAD51D RAD51D-associated hereditary cancer x
RET Multiple endocrine neoplasia, type 2 x x
SMAD4 Juvenile polyposis x x
STK11 Peutz-Jeghers x x x x x x
TP53 Li-Fraumeni syndrome x o o x x x o x x
VHL Von Hippel-Lindau x
Additional Expanded Panel genes
BARD1 BARD1-associated hereditary cancer o o
MEN1 Multiple endocrine neoplasia, type 1 x
MRE11A MRE11A-associated hereditary cancer o o
RAD50 RAD50-associated hereditary cancer o o
SDHA Hereditary paraganglioma-pheochromocytoma x
SDHB Hereditary paraganglioma-pheochromocytoma x
SDHC Hereditary paraganglioma-pheochromocytoma x
X = Associated cancer risk, O = Associated cancer risk with limited or conflicting evidence

Table not representative of all possible cancer risks.

Counsyl Reliant Cancer Screen Panels

Select one of the panel options below, or create a custom panel with any other combination of genes.

Comprehensive Panel

Includes 29 genes with clear cancer risks and patient management guidelines.

  • APC
  • ATM
  • BMPR1A
  • BRCA1
  • BRCA2
  • BRIP1
  • CDH1
  • CDK4
  • CDKN2A
  • CHEK2
  • EPCAM
  • GREM1
  • MLH1
  • MSH2
  • MSH6
  • MUTYH
  • NBN
  • PALB2
  • PMS2
  • POLD1
  • POLE
  • PTEN
  • RAD51C
  • RAD51D
  • RET
  • SMAD4
  • STK11
  • TP53
  • VHL
Breast/Gyn

Includes 19 genes from the Comprehensive Panel that are associated with breast, ovarian, endometrial and other gynecologic cancers.

  • ATM
  • BRCA1
  • BRCA2
  • BRIP1
  • CDH1
  • CHEK2
  • EPCAM
  • MLH1
  • MSH2
  • MSH6
  • NBN
  • PALB2
  • PMS2
  • POLD1
  • PTEN
  • RAD51C
  • RAD51D
  • STK11
  • TP53
Gastrointestinal Panel

Includes 17 genes from the Comprehensive Panel that are associated with gastric, colorectal, and other gastroenterological cancers.

  • APC
  • BMPR1A
  • CDH1
  • CHEK2
  • EPCAM
  • GREM1
  • MLH1
  • MSH2
  • MSH6
  • MUTYH
  • PMS2
  • POLD1
  • POLE
  • PTEN
  • SMAD4
  • STK11
  • TP53
Expanded Panel

Includes all genes from the Comprehensive Panel plus these 7 additional genes.

  • BARD1
  • MEN1
  • MRE11A
  • RAD50
  • SDHA
  • SDHB
  • SDHC
Breast Panel

Includes genes from the Comprehensive Panel associated with breast cancer.

  • ATM
  • BRCA1
  • BRCA2
  • CDH1
  • CHEK2
  • NBN
  • PALB2
  • PTEN
  • STK11
  • TP53
BRCA Panel

Full sequencing of BRCA1 and BRCA2, including large deletions and duplications.

  • BRCA1
  • BRCA2
Gynecologic Panel

Includes genes from the Comprehensive Panel associated with ovarian, endometrial, and other gynecologic cancers.

  • BRCA1
  • BRCA2
  • BRIP1
  • EPCAM
  • MLH1
  • MSH2
  • MSH6
  • PMS2
  • POLD1
  • PTEN
  • RAD51C
  • RAD51D
  • STK11
  • TP53
Lynch Syndrome Panel

Includes genes from the Comprehensive Panel associated with Lynch Syndrome.

  • EPCAM
  • MLH1
  • MSH2
  • MSH6
  • PMS2
Pancreatic Panel

Includes genes from the Comprehensive Panel associated with pancreatic cancers.

  • APC
  • ATM
  • BRCA1
  • BRCA2
  • CDKN2A
  • EPCAM
  • MLH1
  • MSH2
  • MSH6
  • PALB2
  • PMS2
  • STK11
  • TP53
Melanoma Panel

Includes genes associated with neuroendocrine tumors

  • MEN1
  • RET
  • SDHA
  • SDHB
  • SDHC
  • VHL